In-process analysis is a crucial component of successful process development. Lacamas has the following in-process analytical techniques at its disposal:
- HPLC
- GC
- NMR
- UV / vis
- FTIR
As part of developing a sound understanding of the reaction profile and kinetics of our process, we try to develop a mass balance early on. To do this we rely heavily on the use of assays using both internal and external standards as appropriate. All our R&D chemists are well trained and familiar with quantitative chromatographic techniques and, for example, the routine generation of calibration curves to establish linearity of response.
An early understanding of the mass balance of our process underpins the entire development exercise and validation of the economics and environmental impact of the process.